C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000409111 HECW2-002 ENSG00000138411 9606 - 2:196199251-196362222 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000409111
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000409111 0.906±0.00 0.833±0.00 0.739±0.00 0.800±0.00 0.505±0.22 0.132±0.03 2.061±0.37 1.030±0.00 0.402±0.18 5.909±0.00 0.061±0.04 0.527±0.25 1.950±0.40 1.327±0.27

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002KD CIL_0002KD_0001 CGP 2:196133566-196593692
CIL_0002KC CIL_0002KC_0001 CGP 2:196194370-196763490

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004842 IBA:IEA ubiquitin-protein transferase activity
GO:0005515 IEA protein binding
GO:0005634 IBA nucleus
GO:0005737 IBA cytoplasm
GO:0016874 IEA ligase activity
GO:0042787 IBA protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000087659 Hecw2-201 protein_coding Mus_musculus 0 6120
ENSMUST00000120904 Hecw2-001 protein_coding Mus_musculus 0 6120
ENSDART00000090286 HECW2 (2 of 2)-201 protein_coding Danio_rerio 0 1147
ENSMUST00000152870 Hecw2-003 processed_transcript Mus_musculus 0 785
ENSMUST00000150677 Hecw2-004 processed_transcript Mus_musculus 0 396
ENSMUST00000097741 Hecw2-202 protein_coding Mus_musculus 0 392
ENSMUST00000146850 Hecw2-002 retained_intron Mus_musculus 0 302

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