C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000409304 SERPINE2-002 ENSG00000135919 9606 - 2:223975112-224039288 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000409304
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000409304 15.272±0.00 16.709±0.00 37.839±22.31 2.191±1.14 10.319±9.49 3.282±2.51 15.510±0.00 1.691±0.79 3.525±3.39 0.081±0.03 58.799±55.67 910.882±480.95 34.618±9.19

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006XP CIL_0006XP_0001 CGP 2:223957404-224039319
CIL_0006XO CIL_0006XO_0001 CGP 2:223975112-224402085

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004867 IDA serine-type endopeptidase inhibitor activity
GO:0005102 IPI receptor binding
GO:0005515 IPI protein binding
GO:0005539 IDA glycosaminoglycan binding
GO:0005576 IDA extracellular region
GO:0005615 IEA:IBA extracellular space
GO:0005829 IDA cytosol
GO:0008201 IDA heparin binding
GO:0010757 IMP negative regulation of plasminogen activation
GO:0010951 IBA negative regulation of endopeptidase activity
GO:0010955 IC negative regulation of protein processing
GO:0030195 IDA negative regulation of blood coagulation
GO:0030334 NAS regulation of cell migration
GO:0031012 IDA extracellular matrix
GO:0031091 IDA platelet alpha granule
GO:0031232 IDA extrinsic component of external side of plasma membrane
GO:0031594 ISS neuromuscular junction
GO:0031982 IDA vesicle
GO:0045861 IDA negative regulation of proteolysis
GO:0048711 IDA positive regulation of astrocyte differentiation
GO:0090331 ISS negative regulation of platelet aggregation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000027467 Serpine2-001 protein_coding Mus_musculus 0 1317
ENSMUST00000189793 Serpine2-004 protein_coding Mus_musculus 0 745

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