C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info

Description: major histocompatibility complex, class II, DP beta 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000418931 HLA-DPB1-001 ENSG00000223865 9606 + 6:33075926-33087201 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000418931
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000418931 35.433±0.00 173.370±0.00 6.476±0.00 8.435±6.43 37.670±22.90 11.915±7.47 9.862±5.62 16.045±7.37 6.425±3.60 48.926±0.00 3.129±0.00 21.239±18.47 13.836±0.00 11.384±7.24

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001PI CIL_0001PI_0002 CGP 6:33004178-33080775
CIL_0001PL CIL_0001PL_0008 CGP 6:33064569-33087201

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000139 TAS Golgi membrane
GO:0005515 IEA protein binding
GO:0005765 TAS lysosomal membrane
GO:0005768 IEA endosome
GO:0005886 TAS plasma membrane
GO:0006955 IEA immune response
GO:0009986 IMP cell surface
GO:0012507 TAS ER to Golgi transport vesicle membrane
GO:0016020 IDA:IEA membrane
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0019882 IEA antigen processing and presentation
GO:0019886 IMP antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0030658 TAS transport vesicle membrane
GO:0030666 TAS endocytic vesicle membrane
GO:0030669 TAS clathrin-coated endocytic vesicle membrane
GO:0031295 TAS T cell costimulation
GO:0032588 TAS trans-Golgi network membrane
GO:0032729 IMP positive regulation of interferon-gamma production
GO:0042102 IMP positive regulation of T cell proliferation
GO:0042605 IDA peptide antigen binding
GO:0042613 IDA:IEA MHC class II protein complex
GO:0050852 TAS T cell receptor signaling pathway
GO:0050870 IMP positive regulation of T cell activation
GO:0060333 TAS interferon-gamma-mediated signaling pathway
GO:0071556 TAS integral component of lumenal side of endoplasmic reticulum membrane

Homologs

No Homologs available.

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