C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: major histocompatibility complex, class II, DP alpha 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000419277 HLA-DPA1-001 ENSG00000231389 9606 - 6:33064569-33080710 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonKidneyLiverMuscleOvaryPlacentaTestisENST00000419277
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Kidney Liver Muscle Ovary Placenta Testis
ENST00000419277 51.597±0.00 220.062±0.00 4.861±0.00 2.608±0.00 33.429±23.17 6.659±0.00 8.885±0.00 6.811±0.00 1.688±0.00 13.267±7.30 15.643±2.01 12.435±7.46

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001PI CIL_0001PI_0002 CGP 6:33004178-33080775
CIL_0001PL CIL_0001PL_0008 CGP 6:33064569-33087201

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000139 TAS Golgi membrane
GO:0002504 IEA antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
GO:0005515 IEA protein binding
GO:0005765 TAS lysosomal membrane
GO:0005768 IEA endosome
GO:0005886 TAS plasma membrane
GO:0005887 NAS integral component of plasma membrane
GO:0006955 IEA:NAS immune response
GO:0009986 IMP cell surface
GO:0012507 TAS ER to Golgi transport vesicle membrane
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0019882 IEA antigen processing and presentation
GO:0019886 IMP antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0030658 TAS transport vesicle membrane
GO:0030666 TAS endocytic vesicle membrane
GO:0030669 TAS clathrin-coated endocytic vesicle membrane
GO:0031295 TAS T cell costimulation
GO:0032395 NAS MHC class II receptor activity
GO:0032588 TAS trans-Golgi network membrane
GO:0032729 IMP positive regulation of interferon-gamma production
GO:0042102 IMP positive regulation of T cell proliferation
GO:0042605 IDA peptide antigen binding
GO:0042613 IEA:IDA MHC class II protein complex
GO:0050852 TAS T cell receptor signaling pathway
GO:0050870 IMP positive regulation of T cell activation
GO:0060333 TAS interferon-gamma-mediated signaling pathway
GO:0071346 IDA cellular response to interferon-gamma
GO:0071556 TAS integral component of lumenal side of endoplasmic reticulum membrane

Homologs

No Homologs available.

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