C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info

Description: Ras protein-specific guanine nucleotide-releasing factor 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000419573 RASGRF1-001 ENSG00000058335 9606 - 15:78959947-79090773 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; PlacentaTestisENST00000419573
Transcript ID Placenta Testis
ENST00000419573 0.178±0.00 0.048±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005085 TAS:IEA guanyl-nucleotide exchange factor activity
GO:0005088 TAS Ras guanyl-nucleotide exchange factor activity
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005515 IEA protein binding
GO:0005622 IEA intracellular
GO:0005829 ISS cytosol
GO:0005886 NAS plasma membrane
GO:0007165 TAS signal transduction
GO:0007264 IEA small GTPase mediated signal transduction
GO:0007268 TAS synaptic transmission
GO:0007616 NAS long-term memory
GO:0008283 IEA cell proliferation
GO:0030426 ISS growth cone
GO:0031175 ISS neuron projection development
GO:0032320 ISS positive regulation of Ras GTPase activity
GO:0032863 ISS activation of Rac GTPase activity
GO:0035020 ISS regulation of Rac protein signal transduction
GO:0035023 IEA regulation of Rho protein signal transduction
GO:0035254 IEA glutamate receptor binding
GO:0043005 NAS neuron projection
GO:0046578 ISS regulation of Ras protein signal transduction
GO:0046579 ISS positive regulation of Ras protein signal transduction
GO:0048167 ISS regulation of synaptic plasticity
GO:0048168 IEA regulation of neuronal synaptic plasticity
GO:0051056 IEA regulation of small GTPase mediated signal transduction
GO:2000310 IEA regulation of N-methyl-D-aspartate selective glutamate receptor activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000034912 Rasgrf1-001 protein_coding Mus_musculus 0 1978
ENSDART00000109257 RASGRF1-001 protein_coding Danio_rerio 0 1153
ENSMUST00000190073 Rasgrf1-004 retained_intron Mus_musculus 0 368
ENSMUST00000034909 Rasgrf1-002 protein_coding Mus_musculus 0 302
ENSMUST00000189545 Rasgrf1-003 protein_coding Mus_musculus 0 302

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