C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: RAS protein-specific guanine nucleotide-releasing factor 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000034912 Rasgrf1-001 ENSMUSG00000032356 10090 + 9:89909909-90026977 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000034912
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000034912 0.180±0.20 1.897±0.63 0.164±0.00 60.495±84.99 2.395±0.41 0.032±0.01 0.015±0.00 0.010±0.00 0.012±0.01 0.192±0.12 0.010±0.00 0.212±0.11 0.352±0.24 0.444±0.22

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000587 CIL_000587_0002 CGP 9:89728249-90026977
CIL_00058A CIL_00058A_0002 CGP 9:89909908-90076089

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005515 IPI protein binding
GO:0005829 IDA cytosol
GO:0007264 IEA small GTPase mediated signal transduction
GO:0008283 IMP cell proliferation
GO:0030426 IDA growth cone
GO:0031175 IDA neuron projection development
GO:0032320 IDA positive regulation of Ras GTPase activity
GO:0032863 IDA activation of Rac GTPase activity
GO:0035020 IDA regulation of Rac protein signal transduction
GO:0035254 IPI glutamate receptor binding
GO:0046578 IDA regulation of Ras protein signal transduction
GO:0046579 ISS positive regulation of Ras protein signal transduction
GO:0048167 ISS regulation of synaptic plasticity
GO:0048168 IMP regulation of neuronal synaptic plasticity
GO:2000310 IGI regulation of N-methyl-D-aspartate selective glutamate receptor activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000109257 RASGRF1-001 protein_coding Danio_rerio 0 1391
ENST00000394745 RASGRF1-003 protein_coding Homo_sapiens 0 1362
ENST00000419573 RASGRF1-001 protein_coding Homo_sapiens 0 1978
ENST00000558480 RASGRF1-002 protein_coding Homo_sapiens 0 3626
ENST00000559926 RASGRF1-009 processed_transcript Homo_sapiens 0 222
ENST00000560334 RASGRF1-004 processed_transcript Homo_sapiens 0 2977
ENST00000560943 RASGRF1-006 retained_intron Homo_sapiens 0 597

Loading