C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: serine/threonine kinase 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000419617 STK3-001 ENSG00000104375 9606 - 8:98454633-98825681 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000419617
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000419617 5.879±0.00 4.318±0.00 2.975±0.00 1.243±0.24 4.515±0.28 4.854±2.68 2.382±0.73 6.275±3.60 5.086±3.07 6.856±0.19 1.559±0.94 8.391±3.30 8.096±1.45 5.879±0.72

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008YL CIL_0008YL_0001 VISTA 8:98116253-98717204

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000287 IDA magnesium ion binding
GO:0004672 TAS:IEA protein kinase activity
GO:0004674 IDA:IEA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IDA:IEA ATP binding
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0006468 IDA:IEA protein phosphorylation
GO:0006915 TAS apoptotic process
GO:0007165 TAS:IEA signal transduction
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0035329 TAS hippo signaling
GO:0035556 IDA intracellular signal transduction
GO:0043065 ISS positive regulation of apoptotic process
GO:0043539 TAS protein serine/threonine kinase activator activity
GO:0046983 ISS protein dimerization activity
GO:0071902 TAS positive regulation of protein serine/threonine kinase activity
GO:0090090 IMP negative regulation of canonical Wnt signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000018476 Stk3-001 protein_coding Mus_musculus 0 1975
ENSMUST00000067033 Stk3-002 protein_coding Mus_musculus 0 1546
ENSDART00000008698 stk3-001 protein_coding Danio_rerio 0 939
ENSMUST00000138841 Stk3-003 nonsense_mediated_decay Mus_musculus 0 911

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