C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: myocardin
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000425538 MYOCD-001 ENSG00000141052 9606 + 17:12665989-12768949 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000425538
Transcript ID Adipose Adrenal Bladder Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000425538 1.328±0.00 0.571±0.00 0.038±0.00 0.621±0.00 4.507±3.41 2.527±1.07 0.348±0.00 2.235±0.00 1.136±0.00 0.558±0.25 0.573±0.18 3.770±3.34

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007YN CIL_0007YN_0001 VISTA 17:12172466-12773269
CIL_0008QC CIL_0008QC_0001 VISTA 17:12429509-13031929

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0001046 IDA core promoter sequence-specific DNA binding
GO:0001076 ISS RNA polymerase II transcription factor binding transcription factor activity
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001560 IEA regulation of cell growth by extracellular stimulus
GO:0001570 IEA vasculogenesis
GO:0001666 IEP response to hypoxia
GO:0003231 IEA cardiac ventricle development
GO:0003257 IDA positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation
GO:0003713 IEA transcription coactivator activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0006357 IEA regulation of transcription from RNA polymerase II promoter
GO:0006366 IEA transcription from RNA polymerase II promoter
GO:0007507 IEA heart development
GO:0008134 IPI transcription factor binding
GO:0008284 IEA positive regulation of cell proliferation
GO:0008285 IDA negative regulation of cell proliferation
GO:0010667 IEA negative regulation of cardiac muscle cell apoptotic process
GO:0010832 IEA negative regulation of myotube differentiation
GO:0030511 IEA positive regulation of transforming growth factor beta receptor signaling pathway
GO:0035035 IEA histone acetyltransferase binding
GO:0035051 NAS cardiocyte differentiation
GO:0035065 ISS regulation of histone acetylation
GO:0035733 IEA hepatic stellate cell activation
GO:0042692 IEA muscle cell differentiation
GO:0042826 IEA histone deacetylase binding
GO:0043388 IEA positive regulation of DNA binding
GO:0043954 IEA cellular component maintenance
GO:0045661 IEA regulation of myoblast differentiation
GO:0045736 IDA negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0045987 IDA positive regulation of smooth muscle contraction
GO:0048286 IEA lung alveolus development
GO:0048565 IEA digestive tract development
GO:0051091 IDA positive regulation of sequence-specific DNA binding transcription factor activity
GO:0051145 IMP smooth muscle cell differentiation
GO:0051150 TAS regulation of smooth muscle cell differentiation
GO:0051152 IDA positive regulation of smooth muscle cell differentiation
GO:0055007 ISS cardiac muscle cell differentiation
GO:0055012 IEA ventricular cardiac muscle cell differentiation
GO:0060065 IEA uterus development
GO:0060157 IEA urinary bladder development
GO:0061049 IEA cell growth involved in cardiac muscle cell development
GO:0070412 IEA R-SMAD binding
GO:0071363 IEA cellular response to growth factor stimulus
GO:0071456 IEA cellular response to hypoxia
GO:0097070 IEA ductus arteriosus closure
GO:1900222 IMP negative regulation of beta-amyloid clearance
GO:2000721 IDA positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation
GO:2000724 ISS positive regulation of cardiac vascular smooth muscle cell differentiation
GO:2000727 IDA positive regulation of cardiac muscle cell differentiation
GO:2001015 IDA negative regulation of skeletal muscle cell differentiation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000108695 Myocd-201 protein_coding Mus_musculus 0 1724
ENSMUST00000101042 Myocd-002 protein_coding Mus_musculus 0 1683
ENSMUST00000102635 Myocd-001 protein_coding Mus_musculus 0 1090
ENSMUST00000144399 Myocd-005 protein_coding Mus_musculus 0 424
ENSMUST00000150823 Myocd-004 processed_transcript Mus_musculus 0 313

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