C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: Sp1 transcription factor
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000426431 SP1-002 ENSG00000185591 9606 + 12:53380639-53416446 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000426431
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000426431 16.692±0.00 7.278±0.00 1.742±0.00 2.722±2.39 5.685±2.36 4.329±2.15 2.642±0.72 7.675±0.00 3.765±2.21 8.166±0.18 7.329±3.54 7.206±5.52 5.614±0.58 12.981±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00060O CIL_00060O_0001 CGP 12:53326575-53416446
CIL_0001W1 CIL_0001W1_0001 CGP 12:53380176-53431534

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000978 ISS RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001046 ISS core promoter sequence-specific DNA binding
GO:0001103 ISS RNA polymerase II repressing transcription factor binding
GO:0003677 IDA DNA binding
GO:0003690 IDA double-stranded DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IEA cytoplasm
GO:0006351 TAS transcription, DNA-templated
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0007179 TAS transforming growth factor beta receptor signaling pathway
GO:0008022 IPI protein C-terminus binding
GO:0008134 IPI transcription factor binding
GO:0010467 TAS gene expression
GO:0016032 IEA viral process
GO:0042803 IDA protein homodimerization activity
GO:0042826 IPI histone deacetylase binding
GO:0043425 ISS bHLH transcription factor binding
GO:0043565 IDA sequence-specific DNA binding
GO:0043923 IDA positive regulation by host of viral transcription
GO:0044212 IDA transcription regulatory region DNA binding
GO:0044255 TAS cellular lipid metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding
GO:0048511 IEA rhythmic process
GO:0071837 IPI HMG box domain binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000001326 Sp1-001 protein_coding Mus_musculus 0 3792
ENSMUST00000165924 Sp1-005 protein_coding Mus_musculus 0 3792
ENSMUST00000163709 Sp1-008 protein_coding Mus_musculus 0 2194
ENSMUST00000165837 Sp1-003 protein_coding Mus_musculus 0 787
ENSMUST00000168802 Sp1-004 protein_coding Mus_musculus 0 459

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