C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: deiodinase, iodothyronine, type II
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000438257 DIO2-002 ENSG00000211448 9606 - 14:80197530-80211627 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000438257
Transcript ID Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000438257 0.428±0.00 5.257±3.69 4.906±0.00 0.300±0.00 0.939±0.26 0.180±0.17 0.271±0.00 0.216±0.07 0.264±0.00 2.342±2.19 2.535±1.44 1.069±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004U0 CIL_0004U0_0001 CGP 14:78242391-80387757
CIL_0004TZ CIL_0004TZ_0001 CGP 14:80197527-80959517

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001514 NAS selenocysteine incorporation
GO:0004800 IEA:IDA thyroxine 5'-deiodinase activity
GO:0005886 TAS plasma membrane
GO:0006590 TAS thyroid hormone generation
GO:0008430 IC selenium binding
GO:0016020 IC membrane
GO:0016021 IEA integral component of membrane
GO:0016209 IEA antioxidant activity
GO:0016491 IEA oxidoreductase activity
GO:0031625 IPI ubiquitin protein ligase binding
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0042403 IDA thyroid hormone metabolic process
GO:0042446 IEA hormone biosynthetic process
GO:0044281 TAS small molecule metabolic process
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000082432 Dio2-201 protein_coding Mus_musculus 0 1075

Loading