C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: BCL2 binding component 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000439096 BBC3-003 ENSG00000105327 9606 - 19:47220827-47231194 protein_coding

Homo sapiens EnsemblGRCh38

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Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000439096
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000439096 3.706±0.00 2.057±0.00 0.270±0.00 2.308±0.00 4.217±0.00 0.765±0.00 1.347±0.00 0.468±0.00 26.409±0.00 11.923±0.00 6.419±1.41 2.445±1.33 1.697±0.21

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008G1 CIL_0008G1_0001 VISTA 19:46806794-47408636

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001836 IDA release of cytochrome c from mitochondria
GO:0005515 IPI protein binding
GO:0005739 IDA mitochondrion
GO:0005741 TAS mitochondrial outer membrane
GO:0005829 TAS cytosol
GO:0006915 TAS apoptotic process
GO:0006919 IDA activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006974 ISS cellular response to DNA damage stimulus
GO:0008340 ISS determination of adult lifespan
GO:0032464 IDA positive regulation of protein homooligomerization
GO:0032471 IDA negative regulation of endoplasmic reticulum calcium ion concentration
GO:0034976 IDA response to endoplasmic reticulum stress
GO:0043525 ISS positive regulation of neuron apoptotic process
GO:0045926 IMP negative regulation of growth
GO:0051209 IDA release of sequestered calcium ion into cytosol
GO:0070059 ISS intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0070245 ISS positive regulation of thymocyte apoptotic process
GO:0071456 IEP cellular response to hypoxia
GO:0090200 IDA positive regulation of release of cytochrome c from mitochondria
GO:0097190 IDA apoptotic signaling pathway
GO:0097193 TAS intrinsic apoptotic signaling pathway
GO:0097194 IDA execution phase of apoptosis
GO:1900740 IDA positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
GO:2001056 ISS positive regulation of cysteine-type endopeptidase activity
GO:2001244 IMP positive regulation of intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000002152 Bbc3-001 protein_coding Mus_musculus 0 1879
ENSMUST00000147267 Bbc3-003 processed_transcript Mus_musculus 0 784
ENSMUST00000136781 Bbc3-002 protein_coding Mus_musculus 0 486

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