C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: amyloid beta (A4) precursor protein
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000439274 APP-015 ENSG00000142192 9606 - 21:25881332-26170654 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000439274
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000439274 89.423±0.00 79.155±0.00 30.189±0.00 217.694±0.00 27.081±6.18 54.866±40.87 46.747±0.00 84.949±69.63 20.100±0.00 84.131±0.00 13.412±0.00 65.100±32.27 112.935±58.10 56.504±0.17

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000MM CIL_0000MM_0002 CGP 21:25734570-26171128
CIL_0000RE CIL_0000RE_0001 CGP 21:25880550-26573284

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004867 IEA serine-type endopeptidase inhibitor activity
GO:0005794 IDA Golgi apparatus
GO:0007399 IEA nervous system development
GO:0008201 IEA heparin binding
GO:0010951 IEA negative regulation of endopeptidase activity
GO:0016021 IEA integral component of membrane
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0046914 IEA transition metal ion binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000005406 App-201 protein_coding Mus_musculus 0 1943

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