C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: complement component 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000442278 C2-010 ENSG00000166278 9606 + 6:31927496-31945671 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; LungOvaryPlacentaENST00000442278
Transcript ID Lung Ovary Placenta
ENST00000442278 3.188±0.00 13.649±8.91 12.625±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000421 CIL_000421_0001 CGP 6:31897785-31945672

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003824 IEA catalytic activity
GO:0004252 IEA serine-type endopeptidase activity
GO:0005576 TAS:IEA extracellular region
GO:0005615 TAS extracellular space
GO:0006508 IEA proteolysis
GO:0006956 IMP:IEA complement activation
GO:0006958 IEA complement activation, classical pathway
GO:0030449 TAS regulation of complement activation
GO:0045087 TAS innate immune response
GO:0046872 IEA metal ion binding
GO:0070062 IDA extracellular vesicular exosome
GO:2000427 IMP positive regulation of apoptotic cell clearance

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000152417 C2-002 protein_coding Mus_musculus 0 1308
ENSMUST00000025230 C2-001 protein_coding Mus_musculus 0 1284
ENSMUST00000148431 C2-004 protein_coding Mus_musculus 0 911
ENSMUST00000146299 Gm20547-001 protein_coding Mus_musculus 0 784
ENSMUST00000129891 Gm20547-002 protein_coding Mus_musculus 0 481
ENSMUST00000127795 C2-005 retained_intron Mus_musculus 0 366

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