C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: DCC netrin 1 receptor
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000442544 DCC-001 ENSG00000187323 9606 + 18:52340172-53535899 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainOvaryENST00000442544
Transcript ID Adipose Brain Ovary
ENST00000442544 0.005±0.00 0.455±0.00 0.029±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008ER CIL_0008ER_0001 VISTA 18:51746215-52348141

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001764 IEA neuron migration
GO:0001975 IEA response to amphetamine
GO:0003713 IEA transcription coactivator activity
GO:0004888 TAS transmembrane signaling receptor activity
GO:0005042 IEA netrin receptor activity
GO:0005515 IPI:IEA protein binding
GO:0005829 TAS cytosol
GO:0005886 TAS plasma membrane
GO:0006915 TAS apoptotic process
GO:0007409 TAS axonogenesis
GO:0007411 TAS axon guidance
GO:0010976 IEA positive regulation of neuron projection development
GO:0010977 TAS negative regulation of neuron projection development
GO:0016021 IEA integral component of membrane
GO:0021965 IEA spinal cord ventral commissure morphogenesis
GO:0030424 IEA axon
GO:0032584 IEA growth cone membrane
GO:0033563 IEA dorsal/ventral axon guidance
GO:0033564 IEA anterior/posterior axon guidance
GO:0038007 IEA netrin-activated signaling pathway
GO:0042802 IEA identical protein binding
GO:0042981 TAS regulation of apoptotic process
GO:0043065 TAS positive regulation of apoptotic process
GO:0045121 IEA membrane raft
GO:0048671 TAS negative regulation of collateral sprouting
GO:0070374 IEA positive regulation of ERK1 and ERK2 cascade
GO:1901214 IMP regulation of neuron death
GO:2000171 TAS negative regulation of dendrite development
GO:2001141 IEA regulation of RNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000114943 Dcc-001 protein_coding Mus_musculus 0 6248
ENSMUST00000073379 Dcc-002 protein_coding Mus_musculus 0 3729
ENSMUST00000126030 Dcc-003 retained_intron Mus_musculus 0 1062

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