C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: three prime repair exonuclease 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000444177 TREX1-004 ENSG00000213689 9606 + 3:48465946-48467643 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastLungMuscleOvaryPlacentaENST00000444177
Transcript ID Adipose Brain Breast Lung Muscle Ovary Placenta
ENST00000444177 2.651±0.00 3.585±0.00 4.207±0.00 6.930±0.00 3.129±0.00 3.637±0.00 5.910±1.37

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002UL CIL_0002UL_0001 CGP 3:48446710-48467645

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000738 IEA DNA catabolic process, exonucleolytic
GO:0003676 IEA nucleic acid binding
GO:0003697 TAS single-stranded DNA binding
GO:0004527 IEA exonuclease activity
GO:0005634 IDA nucleus
GO:0005635 NAS nuclear envelope
GO:0005730 IDA nucleolus
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006259 ISS DNA metabolic process
GO:0006260 NAS DNA replication
GO:0006281 TAS DNA repair
GO:0006298 NAS mismatch repair
GO:0006310 NAS DNA recombination
GO:0008219 IEA cell death
GO:0008296 ISS 3'-5'-exodeoxyribonuclease activity
GO:0008408 IDA 3'-5' exonuclease activity
GO:0008853 IEA exodeoxyribonuclease III activity
GO:0032405 IDA MutLalpha complex binding
GO:0032407 IDA MutSalpha complex binding
GO:0032479 TAS regulation of type I interferon production
GO:0032481 TAS positive regulation of type I interferon production
GO:0042803 NAS protein homodimerization activity
GO:0045087 TAS innate immune response
GO:0046872 NAS metal ion binding
GO:0090305 IDA nucleic acid phosphodiester bond hydrolysis

Homologs

No Homologs available.

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