C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: discs, large homolog 1 (Drosophila)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000448528 DLG1-007 ENSG00000075711 9606 - 3:197044551-197298576 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; KidneyENST00000448528
Transcript ID Kidney
ENST00000448528 3.160±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001772 TAS immunological synapse
GO:0001935 IDA endothelial cell proliferation
GO:0004385 TAS guanylate kinase activity
GO:0004721 TAS phosphoprotein phosphatase activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005783 IDA endoplasmic reticulum
GO:0005794 IDA Golgi apparatus
GO:0005829 TAS cytosol
GO:0005874 IDA microtubule
GO:0005886 TAS plasma membrane
GO:0005911 IDA cell-cell junction
GO:0005923 IDA tight junction
GO:0007015 IDA actin filament organization
GO:0007093 NAS mitotic cell cycle checkpoint
GO:0007163 TAS establishment or maintenance of cell polarity
GO:0007268 TAS synaptic transmission
GO:0007411 TAS axon guidance
GO:0008022 IPI protein C-terminus binding
GO:0008092 TAS cytoskeletal protein binding
GO:0009898 IDA cytoplasmic side of plasma membrane
GO:0014704 TAS intercalated disc
GO:0015459 NAS potassium channel regulator activity
GO:0016032 IEA viral process
GO:0016311 TAS dephosphorylation
GO:0016323 IDA basolateral plasma membrane
GO:0016337 IDA single organismal cell-cell adhesion
GO:0019901 IPI protein kinase binding
GO:0019902 IPI phosphatase binding
GO:0030054 IDA cell junction
GO:0030866 IDA cortical actin cytoskeleton organization
GO:0031434 IPI mitogen-activated protein kinase kinase binding
GO:0042391 IDA regulation of membrane potential
GO:0043268 IDA positive regulation of potassium ion transport
GO:0044325 IPI ion channel binding
GO:0045211 IEA postsynaptic membrane
GO:0045930 IMP negative regulation of mitotic cell cycle
GO:0046939 TAS nucleotide phosphorylation
GO:0048471 IDA perinuclear region of cytoplasm
GO:0070062 IDA extracellular vesicular exosome
GO:0070830 IDA tight junction assembly
GO:0072659 IMP protein localization to plasma membrane
GO:0090004 IDA positive regulation of establishment of protein localization to plasma membrane
GO:0097016 IPI L27 domain binding
GO:0097025 IDA MPP7-DLG1-LIN7 complex
GO:1902305 TAS regulation of sodium ion transmembrane transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000115205 Dlg1-002 protein_coding Mus_musculus 0 3611
ENSMUST00000100001 Dlg1-201 protein_coding Mus_musculus 0 3607
ENSMUST00000115201 Dlg1-007 protein_coding Mus_musculus 0 3511
ENSMUST00000023454 Dlg1-004 protein_coding Mus_musculus 0 2802
ENSMUST00000064477 Dlg1-003 protein_coding Mus_musculus 0 2623
ENSMUST00000115196 Dlg1-006 protein_coding Mus_musculus 0 2063
ENSMUST00000132176 Dlg1-001 nonsense_mediated_decay Mus_musculus 0 1840
ENSDART00000028406 dlg1-001 protein_coding Danio_rerio 0 1221
ENSMUST00000131136 Dlg1-005 protein_coding Mus_musculus 0 859
ENSMUST00000138213 Dlg1-013 retained_intron Mus_musculus 0 547
ENSMUST00000087984 Dlg3-003 protein_coding Mus_musculus 0 466
ENSMUST00000130920 Dlg1-010 nonsense_mediated_decay Mus_musculus 0 448
ENSDART00000024906 dlg1-201 protein_coding Danio_rerio 0 435
ENSMUST00000155847 Dlg1-011 retained_intron Mus_musculus 0 388
ENSMUST00000155958 Dlg1-008 retained_intron Mus_musculus 0 355
ENSMUST00000113735 Dlg3-004 protein_coding Mus_musculus 0 316
ENSMUST00000147863 Dlg3-002 retained_intron Mus_musculus 0 316
ENSMUST00000113736 Dlg3-001 protein_coding Mus_musculus 0 316
ENSMUST00000000901 Dlg3-006 protein_coding Mus_musculus 0 316
ENSDART00000132170 dlg1-003 processed_transcript Danio_rerio 0 311
ENSMUST00000140258 Dlg1-014 retained_intron Mus_musculus 0 272
ENSDART00000137198 dlg1-005 processed_transcript Danio_rerio 4e-36 158

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