C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: zeta-chain (TCR) associated protein kinase 70kDa
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000451498 ZAP70-008 ENSG00000115085 9606 + 2:97734406-97739498 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BreastColonKidneyLungOvaryPlacentaTestisENST00000451498
Transcript ID Breast Colon Kidney Lung Ovary Placenta Testis
ENST00000451498 0.308±0.00 0.202±0.05 0.371±0.00 3.892±0.00 0.645±0.00 0.650±0.29 0.864±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002U8 CIL_0002U8_0001 CGP 2:97655963-97739862
CIL_00029X CIL_00029X_0001 CGP 2:97713560-97995891

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002250 TAS adaptive immune response
GO:0004672 IEA protein kinase activity
GO:0004713 IDA:IEA protein tyrosine kinase activity
GO:0004715 TAS non-membrane spanning protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 NAS:IEA ATP binding
GO:0005737 TAS cytoplasm
GO:0005829 TAS cytosol
GO:0005886 IDA plasma membrane
GO:0006468 IDA:IEA protein phosphorylation
GO:0006955 IDA immune response
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IDA peptidyl-tyrosine phosphorylation
GO:0030217 NAS T cell differentiation
GO:0035556 NAS intracellular signal transduction
GO:0042101 IDA T cell receptor complex
GO:0042110 TAS T cell activation
GO:0042113 TAS B cell activation
GO:0045059 IDA positive thymic T cell selection
GO:0045121 IDA membrane raft
GO:0045582 IDA positive regulation of T cell differentiation
GO:0050852 TAS T cell receptor signaling pathway
GO:0070489 TAS T cell aggregation
GO:0072678 TAS T cell migration

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000190128 Zap70-002 retained_intron Mus_musculus 0 1101
ENSMUST00000027291 Zap70-001 protein_coding Mus_musculus 0 1099

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