C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000453424 MARCH8-002 ENSG00000165406 9606 - 10:45454585-45535394 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderColonKidneyLiverLungOvaryPlacentaTestisENST00000453424
Transcript ID Bladder Colon Kidney Liver Lung Ovary Placenta Testis
ENST00000453424 0.605±0.00 0.993±0.00 0.883±0.00 0.635±0.00 0.978±0.15 0.593±0.21 0.770±0.00 5.880±2.77

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00081B CIL_00081B_0001 VISTA 10:45257434-45860222
CIL_0000X4 CIL_0000X4_0002 CGP 10:45454585-45672780

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000209 IDA protein polyubiquitination
GO:0002376 IEA immune system process
GO:0002495 IEA antigen processing and presentation of peptide antigen via MHC class II
GO:0004842 IDA ubiquitin-protein transferase activity
GO:0005515 IEA protein binding
GO:0005764 IDA lysosome
GO:0005768 IDA endosome
GO:0008270 IEA zinc ion binding
GO:0016021 IEA integral component of membrane
GO:0016874 IEA ligase activity
GO:0031410 IEA cytoplasmic vesicle
GO:0042289 IEA MHC class II protein binding
GO:0045347 IEA negative regulation of MHC class II biosynthetic process
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000123405 March8-009 retained_intron Mus_musculus 0 1194
ENSMUST00000101032 March8-002 protein_coding Mus_musculus 0 931
ENSMUST00000079012 March8-001 protein_coding Mus_musculus 0 931
ENSMUST00000127992 March8-008 retained_intron Mus_musculus 0 809
ENSMUST00000135901 March8-006 protein_coding Mus_musculus 0 686
ENSMUST00000123246 March8-007 retained_intron Mus_musculus 0 451
ENSMUST00000156014 March8-011 processed_transcript Mus_musculus 0 442
ENSMUST00000130445 March8-010 retained_intron Mus_musculus 4e-34 152

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