C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: methyl CpG binding protein 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000453960 MECP2-002 ENSG00000169057 9606 - X:154030234-154097720 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENST00000453960
Transcript ID Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENST00000453960 3.681±0.00 1.278±0.00 1.877±0.00 6.629±5.31 1.610±0.00 1.969±0.00 2.911±0.64 14.459±12.59 10.389±6.87 6.906±0.00 5.713±0.74

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007GC CIL_0007GC_0002 CGP X:154010500-154097755
CIL_0001LD CIL_0001LD_0001 CGP X:154021573-154159032

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 TAS negative regulation of transcription from RNA polymerase II promoter
GO:0000792 IDA heterochromatin
GO:0001662 IEA behavioral fear response
GO:0001666 IEA response to hypoxia
GO:0001964 IEA startle response
GO:0001976 IEA neurological system process involved in regulation of systemic arterial blood pressure
GO:0002087 IEA regulation of respiratory gaseous exchange by neurological system process
GO:0003677 TAS:IEA DNA binding
GO:0003682 IEA chromatin binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0003714 TAS transcription corepressor activity
GO:0003729 IEA mRNA binding
GO:0005515 IPI protein binding
GO:0005615 IDA extracellular space
GO:0005634 IDA:IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005829 IEA cytosol
GO:0006020 IEA inositol metabolic process
GO:0006122 IEA mitochondrial electron transport, ubiquinol to cytochrome c
GO:0006342 IEA chromatin silencing
GO:0006349 IEA regulation of gene expression by genetic imprinting
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006541 IEA glutamine metabolic process
GO:0006576 IEA cellular biogenic amine metabolic process
GO:0007268 IEA synaptic transmission
GO:0007416 IEA synapse assembly
GO:0007420 IEA brain development
GO:0007585 IEA respiratory gaseous exchange
GO:0007612 IEA learning
GO:0007613 IEA memory
GO:0007616 IEA long-term memory
GO:0008104 IEA protein localization
GO:0008134 IEA transcription factor binding
GO:0008211 IEA glucocorticoid metabolic process
GO:0008284 IEA positive regulation of cell proliferation
GO:0008327 IEA methyl-CpG binding
GO:0008344 IEA adult locomotory behavior
GO:0008542 IEA visual learning
GO:0009405 IEA pathogenesis
GO:0009791 IEA post-embryonic development
GO:0010385 IMP double-stranded methylated DNA binding
GO:0010468 IEA regulation of gene expression
GO:0016358 IEA dendrite development
GO:0016571 IEA histone methylation
GO:0016573 IEA histone acetylation
GO:0019230 IEA proprioception
GO:0019233 IEA sensory perception of pain
GO:0019904 IPI protein domain specific binding
GO:0021549 IEA cerebellum development
GO:0021591 IEA ventricular system development
GO:0030182 IEA neuron differentiation
GO:0031061 IEA negative regulation of histone methylation
GO:0031175 IEA neuron projection development
GO:0032048 IEA cardiolipin metabolic process
GO:0033555 IEA multicellular organismal response to stress
GO:0035067 IEA negative regulation of histone acetylation
GO:0035176 IEA social behavior
GO:0035197 IEA siRNA binding
GO:0040029 IEA regulation of gene expression, epigenetic
GO:0042551 IEA neuron maturation
GO:0043524 IEA negative regulation of neuron apoptotic process
GO:0044822 IDA poly(A) RNA binding
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0046470 IEA phosphatidylcholine metabolic process
GO:0047485 IPI protein N-terminus binding
GO:0048167 IEA regulation of synaptic plasticity
GO:0050432 IEA catecholamine secretion
GO:0050884 IEA neuromuscular process controlling posture
GO:0050905 IEA neuromuscular process
GO:0051965 IEA positive regulation of synapse assembly
GO:0060079 IEA regulation of excitatory postsynaptic membrane potential
GO:0060291 IEA long-term synaptic potentiation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000033770 Mecp2-002 protein_coding Mus_musculus 0 2235
ENSMUST00000170481 Mecp2-201 protein_coding Mus_musculus 0 2104
ENSMUST00000100750 Mecp2-001 protein_coding Mus_musculus 0 2104
ENSMUST00000123362 Mecp2-003 protein_coding Mus_musculus 0 1445
ENSMUST00000140399 Mecp2-004 protein_coding Mus_musculus 0 846

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