C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: cyclin-dependent kinase inhibitor 2A
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000494262 CDKN2A-005 ENSG00000147889 9606 - 9:21968182-21995269 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007YE CIL_0007YE_0001 VISTA 9:21773412-22380489
CIL_0007U7 CIL_0007U7_0001 VISTA 9:21778886-22382106
CIL_0007YH CIL_0007YH_0001 VISTA 9:21779916-22382548
CIL_0007YG CIL_0007YG_0001 VISTA 9:21783894-22389830
CIL_0007U8 CIL_0007U8_0001 VISTA 9:21787553-22389799
CIL_00095D CIL_00095D_0001 VISTA 9:21788649-22389830
CIL_000945 CIL_000945_0001 VISTA 9:21789705-22397955
CIL_0008WE CIL_0008WE_0001 VISTA 9:21797850-22401302
CIL_0007YC CIL_0007YC_0001 VISTA 9:21801286-22408086
CIL_00099P CIL_00099P_0001 VISTA 9:21802665-22404754
CIL_0008P9 CIL_0008P9_0001 VISTA 9:21802671-22404650
CIL_00099O CIL_00099O_0001 VISTA 9:21806995-22409801
CIL_0008TL CIL_0008TL_0001 VISTA 9:21807568-22413901
CIL_00094Y CIL_00094Y_0001 VISTA 9:21816988-22419575
CIL_0008SY CIL_0008SY_0001 VISTA 9:21818504-22425326
CIL_0008T0 CIL_0008T0_0001 VISTA 9:21825013-22425357
CIL_00085X CIL_00085X_0001 VISTA 9:21825358-22430491
CIL_00094Z CIL_00094Z_0001 VISTA 9:21827678-22430449
CIL_0008GG CIL_0008GG_0001 VISTA 9:21841068-22443944

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000082 IDA G1/S transition of mitotic cell cycle
GO:0000278 TAS mitotic cell cycle
GO:0001953 IMP negative regulation of cell-matrix adhesion
GO:0004861 IDA cyclin-dependent protein serine/threonine kinase inhibitor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0007050 IDA cell cycle arrest
GO:0007265 IEP Ras protein signal transduction
GO:0008285 IDA negative regulation of cell proliferation
GO:0019901 IPI protein kinase binding
GO:0030308 IDA negative regulation of cell growth
GO:0032088 IDA negative regulation of NF-kappaB transcription factor activity
GO:0034393 ISS positive regulation of smooth muscle cell apoptotic process
GO:0035985 IDA senescence-associated heterochromatin focus
GO:0035986 IMP senescence-associated heterochromatin focus assembly
GO:0042326 IDA negative regulation of phosphorylation
GO:0044822 IDA poly(A) RNA binding
GO:0045736 IDA negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0045892 IMP negative regulation of transcription, DNA-templated
GO:0051059 IDA NF-kappaB binding
GO:0090398 IMP cellular senescence
GO:0090399 IMP replicative senescence
GO:2000111 ISS positive regulation of macrophage apoptotic process
GO:2000774 IMP positive regulation of cellular senescence

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000107131 Cdkn2a-002 protein_coding Mus_musculus 3e-33 147
ENSMUST00000060501 Cdkn2a-001 protein_coding Mus_musculus 3e-33 147

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