C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info

Description: hematopoietic cell-specific Lyn substrate 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000495491 HCLS1-002 ENSG00000180353 9606 - 3:121632406-121660927 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainColonHeartENST00000495491
Transcript ID Brain Colon Heart
ENST00000495491 7.716±0.00 2.055±0.00 0.192±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00057R CIL_00057R_0002 CGP 3:121631399-121749767

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001085 IPI RNA polymerase II transcription factor binding
GO:0003779 IEA actin binding
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0005667 IDA transcription factor complex
GO:0005737 ISS cytoplasm
GO:0005739 IEA mitochondrion
GO:0006355 TAS regulation of transcription, DNA-templated
GO:0008284 ISS positive regulation of cell proliferation
GO:0009725 ISS response to hormone
GO:0014068 IMP positive regulation of phosphatidylinositol 3-kinase signaling
GO:0016020 IEA membrane
GO:0019901 IPI protein kinase binding
GO:0030041 IEA actin filament polymerization
GO:0030218 ISS erythrocyte differentiation
GO:0030833 IMP regulation of actin filament polymerization
GO:0030854 IMP positive regulation of granulocyte differentiation
GO:0033138 IMP positive regulation of peptidyl-serine phosphorylation
GO:0035556 TAS intracellular signal transduction
GO:0042531 ISS positive regulation of tyrosine phosphorylation of STAT protein
GO:0042993 IMP positive regulation of transcription factor import into nucleus
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0050731 IMP positive regulation of peptidyl-tyrosine phosphorylation
GO:0051897 IMP positive regulation of protein kinase B signaling
GO:0071345 IMP cellular response to cytokine stimulus
GO:2000107 IMP negative regulation of leukocyte apoptotic process
GO:2000251 IC positive regulation of actin cytoskeleton reorganization

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000164050 Hcls1-002 nonsense_mediated_decay Mus_musculus 0 1136
ENSMUST00000023531 Hcls1-001 protein_coding Mus_musculus 0 719
ENSMUST00000163755 Hcls1-003 retained_intron Mus_musculus 0 329

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