C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info

Description: platelet derived growth factor C
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000502773 PDGFC-001 ENSG00000145431 9606 - 4:156760454-156971394 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; ColonHeartENST00000502773
Transcript ID Colon Heart
ENST00000502773 0.460±0.00 0.170±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006DW CIL_0006DW_0002 CGP 4:156760454-157172090

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000139 TAS Golgi membrane
GO:0005161 IPI platelet-derived growth factor receptor binding
GO:0005515 IPI protein binding
GO:0005576 TAS extracellular region
GO:0005615 IDA extracellular space
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0005788 TAS endoplasmic reticulum lumen
GO:0005886 IDA plasma membrane
GO:0007171 IEA activation of transmembrane receptor protein tyrosine kinase activity
GO:0007417 TAS central nervous system development
GO:0008083 IEA growth factor activity
GO:0008284 IEA positive regulation of cell proliferation
GO:0009887 IEA organ morphogenesis
GO:0009986 IDA cell surface
GO:0016020 IEA membrane
GO:0042803 IPI protein homodimerization activity
GO:0045740 IDA positive regulation of DNA replication
GO:0048008 IDA platelet-derived growth factor receptor signaling pathway
GO:0048146 IDA positive regulation of fibroblast proliferation
GO:0050730 IEA regulation of peptidyl-tyrosine phosphorylation
GO:0051781 IEA positive regulation of cell division
GO:0070062 IDA extracellular vesicular exosome
GO:0071230 IEA cellular response to amino acid stimulus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000029652 Pdgfc-001 protein_coding Mus_musculus 0 1543
ENSMUST00000129285 Pdgfc-002 nonsense_mediated_decay Mus_musculus 0 907
ENSMUST00000143721 Pdgfc-003 nonsense_mediated_decay Mus_musculus 0 791

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