C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: potassium inwardly-rectifying channel, subfamily J, member 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000535240 KCNJ2-001 ENSG00000123700 9606 + 17:70168673-70176323 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BreastColonMuscleOvaryENST00000535240
Transcript ID Breast Colon Muscle Ovary
ENST00000535240 0.795±0.00 0.985±0.00 0.616±0.00 0.281±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001L0 CIL_0001L0_0002 CGP 17:70053429-70180048
CIL_00072G CIL_00072G_0001 CGP 17:70168673-72126420

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005242 IDA:IEA inward rectifier potassium channel activity
GO:0005546 IDA phosphatidylinositol-4,5-bisphosphate binding
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006813 IDA:IEA potassium ion transport
GO:0007268 TAS synaptic transmission
GO:0008076 IDA voltage-gated potassium channel complex
GO:0010107 IDA potassium ion import
GO:0014861 IMP regulation of skeletal muscle contraction via regulation of action potential
GO:0016021 IEA integral component of membrane
GO:0030007 TAS cellular potassium ion homeostasis
GO:0031224 IDA intrinsic component of membrane
GO:0051289 IDA protein homotetramerization
GO:0055119 IMP relaxation of cardiac muscle
GO:0060075 TAS regulation of resting membrane potential
GO:0060306 IDA regulation of membrane repolarization
GO:0071805 IDA potassium ion transmembrane transport
GO:0086002 IMP cardiac muscle cell action potential involved in contraction
GO:0086008 IMP voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization
GO:0086011 IMP membrane repolarization during action potential
GO:0086012 TAS membrane depolarization during cardiac muscle cell action potential
GO:0086013 IMP membrane repolarization during cardiac muscle cell action potential
GO:0086091 IMP regulation of heart rate by cardiac conduction
GO:0090076 IMP relaxation of skeletal muscle

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000042970 Kcnj2-001 protein_coding Mus_musculus 0 1694

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