C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: karyopherin (importin) beta 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000535458 KPNB1-002 ENSG00000108424 9606 + 17:47649476-47682633 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000535458
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000535458 12.659±0.00 17.432±0.00 3.278±0.00 5.762±0.00 11.588±3.49 6.433±0.00 14.008±0.00 9.174±0.00 13.733±0.00 11.585±0.00 4.807±0.00 24.699±0.50 18.150±0.00 44.842±10.89

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000060 TAS protein import into nucleus, translocation
GO:0005488 IEA binding
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005635 IDA nuclear envelope
GO:0005643 TAS nuclear pore
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0006309 TAS apoptotic DNA fragmentation
GO:0006606 IDA protein import into nucleus
GO:0006607 TAS NLS-bearing protein import into nucleus
GO:0006610 IDA ribosomal protein import into nucleus
GO:0006915 TAS apoptotic process
GO:0006921 TAS cellular component disassembly involved in execution phase of apoptosis
GO:0008139 TAS nuclear localization sequence binding
GO:0008270 TAS zinc ion binding
GO:0008536 IEA Ran GTPase binding
GO:0016020 IDA membrane
GO:0016032 TAS viral process
GO:0019058 TAS viral life cycle
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0019899 IPI enzyme binding
GO:0019904 IPI protein domain specific binding
GO:0031965 IDA nuclear membrane
GO:0044281 TAS small molecule metabolic process
GO:0044822 IDA poly(A) RNA binding
GO:0070062 IDA extracellular vesicular exosome
GO:0071782 IDA endoplasmic reticulum tubular network
GO:0075733 TAS intracellular transport of virus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000001479 Kpnb1-001 protein_coding Mus_musculus 0 3794
ENSMUST00000132633 Kpnb1-003 retained_intron Mus_musculus 0 627
ENSMUST00000153727 Kpnb1-002 retained_intron Mus_musculus 0 409

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