C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000539978 APPL2-002 ENSG00000136044 9606 - 12:105173935-105233450 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainENST00000539978
Transcript ID Brain
ENST00000539978 0.868±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004G8 CIL_0004G8_0001 CGP 12:105107324-105236238
CIL_0004G6 CIL_0004G6_0001 CGP 12:105173296-105396097

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IC cytoplasm
GO:0007049 IEA cell cycle
GO:0007165 TAS signal transduction
GO:0008283 IDA cell proliferation
GO:0010008 IDA endosome membrane
GO:0016581 IDA NuRD complex
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000020500 Appl2-001 protein_coding Mus_musculus 0 2381
ENSMUST00000147582 Appl2-002 retained_intron Mus_musculus 0 1131
ENSMUST00000176675 Appl2-013 nonsense_mediated_decay Mus_musculus 0 784
ENSMUST00000130285 Appl2-009 retained_intron Mus_musculus 0 736
ENSMUST00000150351 Appl2-012 retained_intron Mus_musculus 0 634
ENSMUST00000146876 Appl2-014 protein_coding Mus_musculus 0 621
ENSMUST00000148096 Appl2-010 retained_intron Mus_musculus 0 593
ENSMUST00000150685 Appl2-005 nonsense_mediated_decay Mus_musculus 0 289
ENSMUST00000141048 Appl2-007 retained_intron Mus_musculus 0 285
ENSMUST00000177187 Appl2-008 protein_coding Mus_musculus 0 270
ENSMUST00000176294 Appl2-003 protein_coding Mus_musculus 1e-25 122

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