C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: interferon regulatory factor 6
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000542854 IRF6-201 ENSG00000117595 9606 - 1:209785623-209806175 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000542854
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000542854 0.258±0.00 0.115±0.00 0.120±0.06 2.407±0.41 2.285±0.52 0.316±0.00 1.717±0.00 1.589±1.14 0.873±0.46 2.298±1.78 3.625±1.81 1.365±0.75

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00089N CIL_00089N_0001 VISTA 1:209189712-209790617
CIL_0007ZL CIL_0007ZL_0001 VISTA 1:209515705-210116479

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000975 IEA regulatory region DNA binding
GO:0003677 ISS DNA binding
GO:0003700 ISS:IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0007050 IDA cell cycle arrest
GO:0008285 IDA negative regulation of cell proliferation
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0060333 TAS interferon-gamma-mediated signaling pathway
GO:0060337 TAS type I interferon signaling pathway
GO:0060644 ISS mammary gland epithelial cell differentiation
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000076521 Irf6-001 protein_coding Mus_musculus 0 1781
ENSMUST00000138826 Irf6-004 retained_intron Mus_musculus 0 636
ENSMUST00000140066 Irf6-002 retained_intron Mus_musculus 0 433
ENSMUST00000160822 A130010J15Rik-003 protein_coding Mus_musculus 1e-37 163

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