C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: large tumor suppressor kinase 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000543571 LATS1-001 ENSG00000131023 9606 - 6:149658153-149718256 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000543571
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000543571 3.203±0.00 0.954±0.00 2.748±0.00 1.734±0.00 1.698±1.23 1.482±0.00 1.950±0.00 0.301±0.00 1.048±0.00 1.542±0.00 1.984±0.82 0.357±0.00 1.843±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000086 IDA G2/M transition of mitotic cell cycle
GO:0000287 IDA magnesium ion binding
GO:0000819 IDA sister chromatid segregation
GO:0000922 IDA spindle pole
GO:0004672 IEA protein kinase activity
GO:0004674 IDA:IEA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IDA:IEA ATP binding
GO:0005829 TAS cytosol
GO:0006468 IDA:IEA protein phosphorylation
GO:0007067 IEA mitotic nuclear division
GO:0009755 ISS hormone-mediated signaling pathway
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0019901 IPI protein kinase binding
GO:0030216 IEA keratinocyte differentiation
GO:0030833 IDA regulation of actin filament polymerization
GO:0033138 IDA positive regulation of peptidyl-serine phosphorylation
GO:0034613 IEA cellular protein localization
GO:0035329 IDA hippo signaling
GO:0043254 IMP regulation of protein complex assembly
GO:0045736 IDA negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0051220 IMP cytoplasmic sequestering of protein
GO:0090090 IMP negative regulation of canonical Wnt signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000165952 Lats1-202 protein_coding Mus_musculus 0 4564
ENSMUST00000040043 Lats1-201 protein_coding Mus_musculus 0 4318

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