C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: large tumor suppressor
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000040043 Lats1-201 ENSMUSG00000040021 10090 + 10:7691247-7713586 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainMuscleOvaryPlacentaTestisENSMUST00000040043
Transcript ID Brain Muscle Ovary Placenta Testis
ENSMUST00000040043 0.835±0.00 0.495±0.00 3.019±0.63 1.327±0.43 3.316±0.55

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000086 ISS G2/M transition of mitotic cell cycle
GO:0000287 ISS magnesium ion binding
GO:0000819 ISS sister chromatid segregation
GO:0000922 ISS spindle pole
GO:0004674 ISS protein serine/threonine kinase activity
GO:0005524 ISS ATP binding
GO:0005737 IEA cytoplasm
GO:0006468 ISS protein phosphorylation
GO:0007067 IEA mitotic nuclear division
GO:0009755 IDA hormone-mediated signaling pathway
GO:0030216 IGI keratinocyte differentiation
GO:0030833 ISS regulation of actin filament polymerization
GO:0034613 IGI cellular protein localization
GO:0035329 IGI hippo signaling
GO:0045736 ISS negative regulation of cyclin-dependent protein serine/threonine kinase activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000253339 LATS1-005 protein_coding Homo_sapiens 0 4318
ENST00000382592 LATS2-001 protein_coding Homo_sapiens 0 453
ENST00000392273 LATS1-003 protein_coding Homo_sapiens 0 2254
ENST00000441107 LATS1-004 nonsense_mediated_decay Homo_sapiens 0 3631
ENST00000458696 LATS1-007 protein_coding Homo_sapiens 0 523
ENST00000542720 LATS1-002 nonsense_mediated_decay Homo_sapiens 0 392
ENST00000542747 LATS1-006 processed_transcript Homo_sapiens 0 3282
ENST00000543571 LATS1-001 protein_coding Homo_sapiens 0 4318

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