C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: large tumor suppressor
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000165952 Lats1-202 ENSMUSG00000040021 10090 + 10:7681209-7716458 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000165952
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000165952 10.486±2.72 12.009±0.89 8.658±0.51 11.423±7.74 11.079±0.82 10.743±0.99 2.744±0.90 9.332±1.44 5.623±0.72 10.734±0.72 1.738±0.32 14.442±3.28 3.353±2.57 3.523±1.65

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000086 ISS G2/M transition of mitotic cell cycle
GO:0000287 ISS magnesium ion binding
GO:0000819 ISS sister chromatid segregation
GO:0000922 ISS spindle pole
GO:0004674 ISS protein serine/threonine kinase activity
GO:0005524 ISS ATP binding
GO:0005737 IEA cytoplasm
GO:0006468 ISS protein phosphorylation
GO:0007067 IEA mitotic nuclear division
GO:0009755 IDA hormone-mediated signaling pathway
GO:0019901 IEA protein kinase binding
GO:0030216 IGI keratinocyte differentiation
GO:0030833 ISS regulation of actin filament polymerization
GO:0033138 IEA positive regulation of peptidyl-serine phosphorylation
GO:0034613 IGI cellular protein localization
GO:0035329 IGI hippo signaling
GO:0043254 IEA regulation of protein complex assembly
GO:0045736 ISS negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0051220 IEA cytoplasmic sequestering of protein
GO:0090090 IEA negative regulation of canonical Wnt signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000253339 LATS1-005 protein_coding Homo_sapiens 0 4453
ENST00000382592 LATS2-001 protein_coding Homo_sapiens 0 453
ENST00000392273 LATS1-003 protein_coding Homo_sapiens 0 2364
ENST00000441107 LATS1-004 nonsense_mediated_decay Homo_sapiens 0 3631
ENST00000458696 LATS1-007 protein_coding Homo_sapiens 0 523
ENST00000542720 LATS1-002 nonsense_mediated_decay Homo_sapiens 0 392
ENST00000542747 LATS1-006 processed_transcript Homo_sapiens 0 3282
ENST00000543571 LATS1-001 protein_coding Homo_sapiens 0 4564

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