C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: epidermal growth factor receptor pathway substrate 8
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000543612 EPS8-004 ENSG00000151491 9606 - 12:15620983-15712993 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; ColonHeartKidneyLungOvaryENST00000543612
Transcript ID Colon Heart Kidney Lung Ovary
ENST00000543612 2.216±0.00 0.616±0.00 1.301±0.00 2.819±0.00 8.013±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005VB CIL_0005VB_0002 CGP 12:15322397-15882329
CIL_0007F9 CIL_0007F9_0001 CGP 12:15620158-15903478

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003779 ISS actin binding
GO:0005070 TAS SH3/SH2 adaptor activity
GO:0005515 IPI:IEA protein binding
GO:0005938 ISS cell cortex
GO:0007165 TAS signal transduction
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0008283 TAS cell proliferation
GO:0008360 ISS regulation of cell shape
GO:0009967 TAS positive regulation of signal transduction
GO:0010458 ISS exit from mitosis
GO:0016601 ISS Rac protein signal transduction
GO:0030054 IEA cell junction
GO:0030832 ISS regulation of actin filament length
GO:0031982 IDA vesicle
GO:0032420 ISS stereocilium
GO:0032587 ISS ruffle membrane
GO:0036336 ISS dendritic cell migration
GO:0043005 IEA neuron projection
GO:0048365 ISS Rac GTPase binding
GO:0051016 ISS barbed-end actin filament capping
GO:0051017 ISS actin filament bundle assembly
GO:0051764 ISS actin crosslink formation
GO:0070062 IDA extracellular vesicular exosome
GO:0070358 ISS actin polymerization-dependent cell motility

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000100841 Eps8-004 protein_coding Mus_musculus 0 2455
ENSMUST00000111878 Eps8-002 protein_coding Mus_musculus 0 2444
ENSMUST00000058210 Eps8-001 protein_coding Mus_musculus 0 2444
ENSMUST00000147526 Eps8-003 protein_coding Mus_musculus 0 1812
ENSMUST00000130274 Eps8-005 processed_transcript Mus_musculus 0 1618
ENSMUST00000132920 Eps8-010 protein_coding Mus_musculus 0 950
ENSMUST00000146442 Eps8-009 protein_coding Mus_musculus 0 641
ENSMUST00000127179 Eps8-011 processed_transcript Mus_musculus 0 385
ENSMUST00000153933 Eps8-008 processed_transcript Mus_musculus 0 326
ENSMUST00000152046 Eps8-012 processed_transcript Mus_musculus 0 219

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