C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: phospholipase C, gamma 2 (phosphatidylinositol-specific)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000564138 PLCG2-001 ENSG00000197943 9606 + 16:81779258-81962693 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverMuscleOvaryPlacentaTestisENST00000564138
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Muscle Ovary Placenta Testis
ENST00000564138 0.981±0.00 6.144±0.00 1.042±0.00 0.155±0.09 1.220±0.00 0.414±0.02 0.098±0.00 0.289±0.00 0.121±0.00 0.112±0.00 0.312±0.09 0.732±0.00 0.645±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003A9 CIL_0003A9_0001 CGP 16:81445170-81962693
CIL_0001Z3 CIL_0001Z3_0001 CGP 16:81739097-82011488

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002316 IEA follicular B cell differentiation
GO:0004435 IEA:IDA phosphatidylinositol phospholipase C activity
GO:0004629 TAS phospholipase C activity
GO:0004871 IEA signal transducer activity
GO:0005515 IPI:IEA protein binding
GO:0005829 TAS cytosol
GO:0005886 IDA plasma membrane
GO:0006629 IEA lipid metabolic process
GO:0006661 IDA phosphatidylinositol biosynthetic process
GO:0007165 IEA signal transduction
GO:0007596 TAS blood coagulation
GO:0008081 IEA phosphoric diester hydrolase activity
GO:0009395 IEA phospholipid catabolic process
GO:0010468 IEA regulation of gene expression
GO:0016055 TAS Wnt signaling pathway
GO:0019722 NAS calcium-mediated signaling
GO:0030168 TAS platelet activation
GO:0030183 ISS B cell differentiation
GO:0032237 IEA activation of store-operated calcium channel activity
GO:0032496 IEA response to lipopolysaccharide
GO:0032959 IEA inositol trisphosphate biosynthetic process
GO:0035556 IEA intracellular signal transduction
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0038096 TAS Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0043069 IEA negative regulation of programmed cell death
GO:0043647 TAS inositol phosphate metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0045087 TAS innate immune response
GO:0050852 ISS T cell receptor signaling pathway
GO:0050853 ISS B cell receptor signaling pathway
GO:0051209 IDA release of sequestered calcium ion into cytosol
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000081232 Plcg2-201 protein_coding Mus_musculus 0 4261

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