C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000564370 STUB1-008 ENSG00000103266 9606 + 16:681037-682496 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastColonLiverMuscleOvaryPlacentaENST00000564370
Transcript ID Brain Breast Colon Liver Muscle Ovary Placenta
ENST00000564370 23.791±0.00 16.747±11.62 23.652±0.00 6.007±0.00 25.399±0.00 47.429±0.00 28.291±14.21

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000151 IDA ubiquitin ligase complex
GO:0000209 IDA protein polyubiquitination
GO:0001664 IPI G-protein coupled receptor binding
GO:0004842 IDA:IEA ubiquitin-protein transferase activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005783 IDA endoplasmic reticulum
GO:0005829 TAS cytosol
GO:0005886 IDA plasma membrane
GO:0006281 IEA DNA repair
GO:0006511 IMP ubiquitin-dependent protein catabolic process
GO:0006515 IDA misfolded or incompletely synthesized protein catabolic process
GO:0007179 TAS transforming growth factor beta receptor signaling pathway
GO:0016567 IEA protein ubiquitination
GO:0016874 IEA ligase activity
GO:0019899 IPI enzyme binding
GO:0019900 IPI kinase binding
GO:0030512 TAS negative regulation of transforming growth factor beta receptor signaling pathway
GO:0030544 IDA Hsp70 protein binding
GO:0030579 IDA ubiquitin-dependent SMAD protein catabolic process
GO:0030674 TAS protein binding, bridging
GO:0030911 IDA TPR domain binding
GO:0031371 TAS ubiquitin conjugating enzyme complex
GO:0031398 IDA positive regulation of protein ubiquitination
GO:0031625 IPI ubiquitin protein ligase binding
GO:0031943 IDA regulation of glucocorticoid metabolic process
GO:0032436 IDA positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0034450 ISS ubiquitin-ubiquitin ligase activity
GO:0042405 IDA nuclear inclusion body
GO:0042803 ISS protein homodimerization activity
GO:0043161 IDA proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0045111 IDA intermediate filament cytoskeleton
GO:0046332 IDA SMAD binding
GO:0051604 TAS protein maturation
GO:0051787 IDA misfolded protein binding
GO:0051865 IDA protein autoubiquitination
GO:0051879 IDA Hsp90 protein binding
GO:0070062 IDA extracellular vesicular exosome
GO:0070534 IDA protein K63-linked ubiquitination
GO:0071218 IDA cellular response to misfolded protein
GO:0090035 IDA positive regulation of chaperone-mediated protein complex assembly

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000044911 Stub1-201 protein_coding Mus_musculus 0 918
ENSDART00000066500 stub1-201 protein_coding Danio_rerio 0 460
ENSDART00000145075 stub1-001 protein_coding Danio_rerio 0 460
ENSMUST00000026832 Jmjd8-201 protein_coding Mus_musculus 5.60519e-45 185
ENSMUST00000133595 Jmjd8-001 protein_coding Mus_musculus 5.60519e-45 185

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