C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: protein tyrosine phosphatase, receptor type, M
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000580170 PTPRM-012 ENSG00000173482 9606 + 18:7566782-8406668 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; HeartMusclePlacentaENST00000580170
Transcript ID Heart Muscle Placenta
ENST00000580170 11.061±0.00 3.291±0.00 2.699±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001937 IMP negative regulation of endothelial cell proliferation
GO:0004725 IDA:IEA protein tyrosine phosphatase activity
GO:0005001 IDA transmembrane receptor protein tyrosine phosphatase activity
GO:0005515 IPI:IEA protein binding
GO:0005737 IDA cytoplasm
GO:0005887 NAS integral component of plasma membrane
GO:0005911 IDA cell-cell junction
GO:0005913 IDA cell-cell adherens junction
GO:0006470 IDA:IEA protein dephosphorylation
GO:0007156 IDA homophilic cell adhesion via plasma membrane adhesion molecules
GO:0007165 IDA signal transduction
GO:0010596 IMP negative regulation of endothelial cell migration
GO:0010842 IMP retina layer formation
GO:0016020 IEA membrane
GO:0016311 IEA dephosphorylation
GO:0016525 IMP negative regulation of angiogenesis
GO:0016791 IEA phosphatase activity
GO:0030027 IDA lamellipodium
GO:0031175 IDA neuron projection development
GO:0031290 IDA retinal ganglion cell axon guidance
GO:0035335 IEA peptidyl-tyrosine dephosphorylation
GO:0042493 IDA response to drug
GO:0042802 IPI identical protein binding
GO:0045296 IDA cadherin binding
GO:0045909 IEA positive regulation of vasodilation
GO:0048471 IDA perinuclear region of cytoplasm

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000037974 Ptprm-201 protein_coding Mus_musculus 0 3131
ENSDART00000148816 PTPRM-001 protein_coding Danio_rerio 0 457
ENSDART00000122795 PTPRM-201 protein_coding Danio_rerio 0 427

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