C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: peptidylprolyl cis/trans isomerase, NIMA-interacting 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000588695 PIN1-008 ENSG00000127445 9606 + 19:9835341-9849682 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLungOvaryTestisENST00000588695
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Lung Ovary Testis
ENST00000588695 26.743±0.00 19.508±0.00 2.531±0.00 35.897±18.93 13.781±12.64 45.383±0.00 2.551±0.00 7.993±5.88 9.554±0.00 15.537±0.00 28.347±15.65

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005J0 CIL_0005J0_0001 CGP 19:9827892-9849682
CIL_0005EY CIL_0005EY_0001 CGP 19:9835257-9936552

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000413 IEA protein peptidyl-prolyl isomerization
GO:0001934 IGI positive regulation of protein phosphorylation
GO:0003755 IDA peptidyl-prolyl cis-trans isomerase activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IEA cytoplasm
GO:0006457 IEA protein folding
GO:0007049 IEA cell cycle
GO:0007088 TAS regulation of mitosis
GO:0016853 IEA isomerase activity
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0030496 IDA midbody
GO:0030512 IDA negative regulation of transforming growth factor beta receptor signaling pathway
GO:0031434 IPI mitogen-activated protein kinase kinase binding
GO:0032321 IMP positive regulation of Rho GTPase activity
GO:0032465 IGI regulation of cytokinesis
GO:0032480 TAS negative regulation of type I interferon production
GO:0032794 IPI GTPase activating protein binding
GO:0045087 TAS innate immune response
GO:0050815 IDA phosphoserine binding
GO:0050816 IDA phosphothreonine binding
GO:0051443 IDA positive regulation of ubiquitin-protein transferase activity
GO:0060393 IDA regulation of pathway-restricted SMAD protein phosphorylation
GO:0070373 IDA negative regulation of ERK1 and ERK2 cascade
GO:2000146 IDA negative regulation of cell motility

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000034689 Pin1-201 protein_coding Mus_musculus 0 606
ENSMUST00000099659 Pin1rt1-001 protein_coding Mus_musculus 0 562

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