C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: sirtuin 5
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000606117 SIRT5-002 ENSG00000124523 9606 + 6:13574643-13614558 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000606117
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000606117 1.473±0.00 0.764±0.00 0.732±0.00 2.018±0.58 0.994±0.11 0.692±0.01 1.558±0.00 1.561±0.61 1.181±0.11 0.293±0.08 1.515±0.07 2.021±0.84 0.796±0.29 1.408±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008MO CIL_0008MO_0001 VISTA 6:13058507-13660102
CIL_0003IA CIL_0003IA_0001 CGP 6:13357830-13615158
CIL_0003I9 CIL_0003I9_0001 CGP 6:13574529-13632739

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IEA protein binding
GO:0005634 TAS nucleus
GO:0005739 IDA mitochondrion
GO:0005758 IDA mitochondrial intermembrane space
GO:0005759 IDA mitochondrial matrix
GO:0005829 IDA cytosol
GO:0006342 TAS chromatin silencing
GO:0006476 IDA protein deacetylation
GO:0008270 IDA zinc ion binding
GO:0036047 IDA peptidyl-lysine demalonylation
GO:0036048 IDA protein desuccinylation
GO:0036049 IDA peptidyl-lysine desuccinylation
GO:0036054 IDA protein-malonyllysine demalonylase activity
GO:0036055 IDA protein-succinyllysine desuccinylase activity
GO:0070403 IDA:IEA NAD+ binding
GO:2000378 IDA negative regulation of reactive oxygen species metabolic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000066804 Sirt5-201 protein_coding Mus_musculus 0 915

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