C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: E2F transcription factor 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000622594 E2F1-201 ENSG00000101412 9606 - 20:33675487-33686404 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; HeartOvaryENST00000622594
Transcript ID Heart Ovary
ENST00000622594 0.015±0.00 0.117±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00003O CIL_00003O_0001 CGP 20:33666498-33686404
CIL_0001NZ CIL_0001NZ_0001 CGP 20:33675487-33720319

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000077 IMP DNA damage checkpoint
GO:0000082 TAS G1/S transition of mitotic cell cycle
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0000278 TAS mitotic cell cycle
GO:0001047 IDA core promoter binding
GO:0003677 IMP DNA binding
GO:0003700 TAS:IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005667 IEA transcription factor complex
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IDA:IEA regulation of transcription, DNA-templated
GO:0006915 TAS apoptotic process
GO:0007219 TAS Notch signaling pathway
GO:0008134 IPI transcription factor binding
GO:0008630 IMP intrinsic apoptotic signaling pathway in response to DNA damage
GO:0010628 IDA positive regulation of gene expression
GO:0035189 IDA Rb-E2F complex
GO:0045892 IMP negative regulation of transcription, DNA-templated
GO:0045893 IMP positive regulation of transcription, DNA-templated
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0048146 IMP positive regulation of fibroblast proliferation
GO:0048255 IDA mRNA stabilization
GO:0071930 IMP negative regulation of transcription involved in G1/S transition of mitotic cell cycle
GO:0097193 TAS intrinsic apoptotic signaling pathway
GO:1900740 TAS positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
GO:2000045 IMP regulation of G1/S transition of mitotic cell cycle

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000103145 E2f1-001 protein_coding Mus_musculus 0 1528
ENSMUST00000000894 E2f1-002 protein_coding Mus_musculus 0 1118
ENSMUST00000061721 E2f2-001 protein_coding Mus_musculus 2e-38 165

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