C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: hepatocyte nuclear factor 4, alpha
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000021494 hnf4a 7955 + 23:26120028-26153195 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000028236 hnf4a-201 26143980-26153189 protein_coding
  ENSDART00000124103 hnf4a-002 26143968-26151305 nonsense_mediated_decay
  ENSDART00000138272 hnf4a-004 26148737-26149636 processed_transcript
  ENSDART00000138907 hnf4a-005 26120028-26148867 protein_coding
  ENSDART00000139049 hnf4a-003 26144009-26144622 retained_intron
  ENSDART00000145426 hnf4a-001 26143880-26153195 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000028236ENSDART00000124103ENSDART00000138272ENSDART00000138907ENSDART00000139049ENSDART00000145426
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000028236 0.041±0.01 0.532±0.15 19.084±8.64 9.719±0.00 0.242±0.00
ENSDART00000124103 N/A N/A 4.489±0.00 5.460±0.00 N/A
ENSDART00000138272 0.324±0.20 0.659±0.00 N/A N/A N/A
ENSDART00000138907 0.186±0.00 0.060±0.00 N/A N/A 0.785±0.00
ENSDART00000139049 1.266±0.00 N/A N/A N/A N/A
ENSDART00000145426 0.414±0.00 0.361±0.00 N/A 2.635±0.00 0.811±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006S2 CIL_0006S2_0001 CGP 23:26108394-26153195
CIL_0002B3 CIL_0002B3_0001 CGP 23:26120028-26162216

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0003707 IEA steroid hormone receptor activity
GO:0004879 IEA ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0005634 IEA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-dependent
GO:0008270 IEA zinc ion binding
GO:0043401 IEA steroid hormone mediated signaling pathway
GO:0043565 IEA sequence-specific DNA binding
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000101076 HNF4A hepatocyte nuclear factor 4, alpha protein_coding Homo_sapiens
ENSMUSG00000017950 Hnf4a hepatic nuclear factor 4, alpha protein_coding Mus_musculus

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