C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: lipoic acid synthetase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000022845 lias 7955 + 1:22048804-22057562 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000036448 lias-001 22048804-22057562 protein_coding
  ENSDART00000144792 lias-002 22049016-22053796 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000036448
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000036448 7.965±4.72 10.222±6.73 6.199±2.00 1.147±0.00 6.945±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002TV CIL_0002TV_0001 CGP 1:22043597-22057562
CIL_000278 CIL_000278_0001 CGP 1:22048804-22068847

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003824 IEA catalytic activity
GO:0005739 IEA mitochondrion
GO:0009107 IEA lipoate biosynthetic process
GO:0016740 IEA transferase activity
GO:0016992 IEA lipoate synthase activity
GO:0046872 IEA metal ion binding
GO:0051536 IEA iron-sulfur cluster binding
GO:0051539 IEA 4 iron, 4 sulfur cluster binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000121897 LIAS lipoic acid synthetase protein_coding Homo_sapiens
ENSMUSG00000029199 Lias lipoic acid synthetase protein_coding Mus_musculus

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