C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: lipoic acid synthetase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000121897 LIAS 9606 + 4:39459000-39477653 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000261434 LIAS-001 39459000-39477653 protein_coding
  ENST00000340169 LIAS-008 39459000-39477584 protein_coding
  ENST00000381846 LIAS-002 39459072-39477621 protein_coding
  ENST00000424936 LIAS-004 39459058-39464163 retained_intron
  ENST00000509519 LIAS-003 39459045-39464238 retained_intron
  ENST00000513731 LIAS-006 39459066-39477155 protein_coding
  ENST00000515061 LIAS-007 39459120-39466072 processed_transcript

Homo sapiens EnsemblGRCh38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000261434ENST00000340169ENST00000381846ENST00000424936ENST00000509519ENST00000513731ENST00000515061
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000261434 N/A 0.513±0.00 N/A 1.548±0.01 N/A 1.184±0.00 1.964±1.22 1.219±0.17 0.969±0.37 N/A 1.991±0.00 2.192±1.23 0.598±0.00 2.097±0.00
ENST00000340169 0.713±0.00 0.807±0.00 N/A 1.488±0.00 2.104±0.00 1.486±0.00 N/A 1.660±0.00 1.045±0.00 0.447±0.00 2.177±0.00 1.810±0.00 1.268±1.00 6.653±3.74
ENST00000381846 0.734±0.00 0.841±0.00 N/A 0.394±0.00 0.306±0.00 2.928±0.00 0.463±0.31 1.003±0.00 0.605±0.03 0.708±0.37 N/A 1.123±0.56 1.176±0.65 1.586±0.00
ENST00000424936 N/A N/A 1.937±0.00 N/A 1.364±0.00 0.469±0.00 N/A 1.129±0.00 N/A N/A N/A 0.794±0.00 N/A N/A
ENST00000509519 N/A N/A N/A N/A N/A N/A N/A N/A 0.697±0.00 0.670±0.00 N/A N/A N/A N/A
ENST00000513731 1.072±0.00 1.130±0.00 N/A 2.294±0.00 1.136±0.00 2.192±0.00 1.417±0.70 N/A 0.649±0.00 1.298±0.00 3.643±0.13 0.545±0.03 0.863±0.00 2.493±0.79
ENST00000515061 N/A N/A N/A N/A N/A N/A N/A 0.783±0.00 N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002TV CIL_0002TV_0002 CGP 4:39454124-39477653
CIL_000278 CIL_000278_0002 CGP 4:39459000-39528311

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001843 IEA neural tube closure
GO:0003824 IEA catalytic activity
GO:0005739 ISS mitochondrion
GO:0006954 ISS inflammatory response
GO:0006979 ISS response to oxidative stress
GO:0009107 ISS:IEA lipoate biosynthetic process
GO:0009249 IEA protein lipoylation
GO:0016992 ISS:IEA lipoate synthase activity
GO:0032496 ISS response to lipopolysaccharide
GO:0046872 IEA metal ion binding
GO:0051536 IEA iron-sulfur cluster binding
GO:0051539 IEA 4 iron, 4 sulfur cluster binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000022845 lias lipoic acid synthetase protein_coding Danio_rerio
ENSMUSG00000029199 Lias lipoic acid synthetase protein_coding Mus_musculus

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