C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: lipoic acid synthetase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000029199 Lias 10090 + 5:65391497-65410693 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000031101 Lias-001 65391497-65410693 protein_coding
  ENSMUST00000122026 Lias-003 65391541-65408950 protein_coding
  ENSMUST00000126036 Lias-004 65391564-65395612 retained_intron
  ENSMUST00000127519 Lias-005 65397542-65399918 retained_intron
  ENSMUST00000139847 Lias-002 65391546-65396183 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000031101ENSMUST00000122026ENSMUST00000126036
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000031101 2.638±0.18 1.578±0.74 3.679±0.22 3.752±0.59 1.760±0.64 2.018±0.31 2.538±0.20 3.122±0.39 2.875±1.14 1.917±0.42 3.164±0.77 2.761±0.90 2.375±0.99 1.973±0.43
ENSMUST00000122026 11.696±3.80 6.018±2.02 9.509±3.47 9.616±4.05 7.577±1.01 7.316±1.58 7.822±3.09 10.564±3.20 11.093±3.08 5.991±0.97 11.991±2.53 8.934±2.72 14.466±2.31 17.339±2.97
ENSMUST00000126036 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 7.644±0.08 8.905±0.31

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002TV CIL_0002TV_0003 CGP 5:65388364-65410693
CIL_000278 CIL_000278_0003 CGP 5:65391497-65435946

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001843 IMP neural tube closure
GO:0005739 IDA mitochondrion
GO:0006954 IMP inflammatory response
GO:0006979 IMP response to oxidative stress
GO:0009107 IGI lipoate biosynthetic process
GO:0009249 IEA protein lipoylation
GO:0016992 IGI lipoate synthase activity
GO:0032496 IMP response to lipopolysaccharide
GO:0046872 IEA metal ion binding
GO:0051539 IEA 4 iron, 4 sulfur cluster binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000022845 lias lipoic acid synthetase protein_coding Danio_rerio
ENSG00000121897 LIAS lipoic acid synthetase protein_coding Homo_sapiens

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