C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: tryptophan hydroxylase 1 (tryptophan 5-monooxygenase) a
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000029432 tph1a 7955 - 25:8402878-8423475 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000041676 tph1a-201 8402884-8423475 protein_coding
  ENSDART00000067159 tph1a-202 8402878-8423475 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000041676ENSDART00000067159
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000041676 1.924±1.40 0.203±0.19 1.272±0.04 0.148±0.00 0.114±0.00
ENSDART00000067159 0.096±0.05 0.071±0.04 N/A 0.026±0.00 0.113±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001IE CIL_0001IE_0001 CGP 25:8349905-8423475
CIL_00041A CIL_00041A_0001 CGP 25:8402878-8465457

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004497 IEA monooxygenase activity
GO:0004510 IEA tryptophan 5-monooxygenase activity
GO:0005506 IEA iron ion binding
GO:0008152 IEA metabolic process
GO:0009072 IEA aromatic amino acid family metabolic process
GO:0016597 IEA amino acid binding
GO:0016714 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen
GO:0042427 IEA serotonin biosynthetic process
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000129167 TPH1 tryptophan hydroxylase 1 protein_coding Homo_sapiens
ENSMUSG00000040046 Tph1 tryptophan hydroxylase 1 protein_coding Mus_musculus

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