C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: E2F transcription factor 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000057323 e2f8 7955 - 7:17351485-17373447 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000079953 e2f8-001 17351491-17372368 protein_coding
  ENSDART00000128488 e2f8-201 17351485-17372148 protein_coding
  ENSDART00000131726 e2f8-004 17352209-17357425 protein_coding
  ENSDART00000134548 e2f8-003 17368269-17372176 protein_coding
  ENSDART00000144118 e2f8-002 17368348-17373447 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000079953ENSDART00000128488ENSDART00000131726ENSDART00000144118
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000079953 N/A N/A 0.496±0.00 N/A N/A
ENSDART00000128488 0.179±0.13 0.840±0.42 3.772±2.24 0.119±0.00 0.026±0.00
ENSDART00000131726 0.143±0.00 N/A N/A N/A N/A
ENSDART00000144118 0.291±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007HT CIL_0007HT_0001 CGP 7:17324640-17373447
CIL_0004AV CIL_0004AV_0001 CGP 7:17351485-17790234

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0001890 ISS placenta development
GO:0002040 IMP sprouting angiogenesis
GO:0003677 IEA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0003714 ISS transcription corepressor activity
GO:0005634 IEA nucleus
GO:0005667 IEA transcription factor complex
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-dependent
GO:0007049 IEA cell cycle
GO:0032466 ISS negative regulation of cytokinesis
GO:0032877 ISS positive regulation of DNA endoreduplication
GO:0033301 ISS cell cycle comprising mitosis without cytokinesis
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0060707 ISS trophoblast giant cell differentiation
GO:0060718 ISS chorionic trophoblast cell differentiation
GO:0070365 ISS hepatocyte differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000129173 E2F8 E2F transcription factor 8 protein_coding Homo_sapiens
ENSMUSG00000046179 E2f8 E2F transcription factor 8 protein_coding Mus_musculus

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