C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Rho guanine nucleotide exchange factor (GEF) 12b
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000067634 arhgef12b 7955 - 5:60164511-60243120 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000087610 arhgef12b-201 60164514-60230293 protein_coding
  ENSDART00000156198 arhgef12b-001 60164511-60243120 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000087610ENSDART00000156198
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000087610 2.852±2.14 7.591±6.80 3.355±1.14 N/A N/A
ENSDART00000156198 4.781±1.35 4.736±1.25 1.920±0.00 0.645±0.00 1.931±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00021U CIL_00021U_0001 CGP 5:60147744-60164937
CIL_0003MJ CIL_0003MJ_0001 CGP 5:60164511-60310224

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005515 IEA protein binding
GO:0005737 IEA cytoplasm
GO:0035023 IEA regulation of Rho protein signal transduction
GO:0038032 IEA termination of G-protein coupled receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000196914 ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 protein_coding Homo_sapiens
ENSMUSG00000059495 Arhgef12 Rho guanine nucleotide exchange factor (GEF) 12 protein_coding Mus_musculus

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