C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: arachidonate 12-lipoxygenase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000069463 alox12 7955 + 7:27155574-27173814 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000101126 alox12-001 27155574-27173814 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000101126
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000101126 0.734±0.33 1.774±0.74 8.616±4.44 0.236±0.00 3.423±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004052 IDA arachidonate 12-lipoxygenase activity
GO:0005506 IEA iron ion binding
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0016491 IEA oxidoreductase activity
GO:0016702 IEA oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
GO:0046872 IEA metal ion binding
GO:0051213 IEA dioxygenase activity
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000108839 ALOX12 arachidonate 12-lipoxygenase protein_coding Homo_sapiens
ENSG00000161905 ALOX15 arachidonate 15-lipoxygenase protein_coding Homo_sapiens
ENSMUSG00000000320 Alox12 arachidonate 12-lipoxygenase protein_coding Mus_musculus
ENSMUSG00000018907 Alox12e arachidonate lipoxygenase, epidermal protein_coding Mus_musculus
ENSMUSG00000018924 Alox15 arachidonate 15-lipoxygenase protein_coding Mus_musculus

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