C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: met proto-oncogene (hepatocyte growth factor receptor)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000070903 met 7955 + 25:19071167-19166361 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000104461 met-201 19074628-19166341 protein_coding
  ENSDART00000148741 met-001 19071167-19166361 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000104461ENSDART00000148741
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000104461 0.035±0.01 0.148±0.04 0.272±0.00 2.174±0.00 N/A
ENSDART00000148741 0.890±0.43 N/A 0.800±0.00 1.456±0.00 0.223±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00063M CIL_00063M_0001 CGP 25:19043878-19180696
CIL_00063L CIL_00063L_0001 CGP 25:19050766-19180696

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0001764 IMP neuron migration
GO:0001889 IMP liver development
GO:0004672 IEA protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0004714 IEA transmembrane receptor protein tyrosine kinase activity
GO:0004872 IEA receptor activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0006468 IEA protein phosphorylation
GO:0007169 IEA transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007275 IEA multicellular organismal development
GO:0016020 IEA membrane
GO:0016021 IEA integral to membrane
GO:0016301 IEA kinase activity
GO:0016310 IEA phosphorylation
GO:0016477 IMP cell migration
GO:0016740 IEA transferase activity
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0021522 IMP spinal cord motor neuron differentiation
GO:0021549 IMP cerebellum development
GO:0021587 IMP cerebellum morphogenesis
GO:0021707 IMP cerebellar granule cell differentiation
GO:0021953 IMP central nervous system neuron differentiation
GO:0031017 IMP exocrine pancreas development
GO:0033339 IMP pectoral fin development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000105976 MET MET proto-oncogene, receptor tyrosine kinase protein_coding Homo_sapiens
ENSMUSG00000009376 Met met proto-oncogene protein_coding Mus_musculus

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