C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cadherin 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000075549 cdh5 7955 + 7:45433470-45486203 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000108766 cdh5-201 45433470-45455664 protein_coding
  ENSDART00000111441 cdh5-202 45433470-45486203 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverENSDART00000108766ENSDART00000111441
Transcript ID Brain Heart Kidney Liver
ENSDART00000108766 1.228±0.00 36.910±27.28 9.362±7.44 N/A
ENSDART00000111441 3.741±1.76 15.783±5.13 2.046±0.00 0.909±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006SB CIL_0006SB_0001 CGP 7:44733496-45486203
CIL_0003BQ CIL_0003BQ_0001 CGP 7:45433470-45568430

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002040 IMP sprouting angiogenesis
GO:0005509 IEA calcium ion binding
GO:0005886 IEA plasma membrane
GO:0007155 IEA cell adhesion
GO:0007156 IEA homophilic cell adhesion
GO:0007507 IMP heart development
GO:0016020 IEA membrane
GO:0016021 IEA integral to membrane
GO:0016525 IMP negative regulation of angiogenesis
GO:0072554 IMP blood vessel lumenization
GO:1902354 IMP blood vessel endothelial cell delamination involved in blood vessel lumen ensheathment
GO:1902355 IMP endothelial tube lumen extension involved in blood vessel lumen ensheathment

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000179776 CDH5 cadherin 5, type 2 (vascular endothelium) protein_coding Homo_sapiens
ENSMUSG00000031871 Cdh5 cadherin 5 protein_coding Mus_musculus

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