C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: transforming, acidic coiled-coil containing protein 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000013810 TACC3 9606 + 4:1721490-1745176 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000313288 TACC3-001 1721539-1745171 protein_coding
  ENST00000404054 TACC3-012 1739351-1742121 retained_intron
  ENST00000458173 TACC3-011 1723110-1728066 protein_coding
  ENST00000466077 TACC3-007 1730803-1737645 retained_intron
  ENST00000467746 TACC3-004 1721535-1728232 nonsense_mediated_decay
  ENST00000470136 TACC3-006 1728404-1735827 protein_coding
  ENST00000470808 TACC3-008 1739345-1741294 retained_intron
  ENST00000484264 TACC3-009 1744439-1745076 retained_intron
  ENST00000484651 TACC3-002 1721519-1738350 retained_intron
  ENST00000485989 TACC3-003 1721500-1735747 protein_coding
  ENST00000493975 TACC3-005 1721785-1728094 protein_coding
  ENST00000612220 TACC3-201 1721490-1745176 protein_coding
  ENST00000617535 TACC3-202 1721545-1745168 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000313288ENST00000404054ENST00000458173ENST00000467746ENST00000470136ENST00000470808ENST00000484264ENST00000484651ENST00000485989ENST00000493975ENST00000617535
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000313288 0.992±0.00 4.584±0.00 N/A 0.434±0.00 0.998±0.00 0.442±0.00 0.603±0.00 N/A N/A 0.345±0.10 N/A 6.110±5.94 10.702±2.40 40.844±19.36
ENST00000404054 N/A N/A N/A N/A N/A N/A N/A 0.207±0.00 0.150±0.00 0.568±0.00 0.044±0.00 N/A N/A N/A
ENST00000458173 N/A N/A N/A 0.217±0.00 1.169±0.00 N/A N/A 1.212±0.00 0.268±0.00 1.065±0.00 N/A 1.155±0.00 N/A N/A
ENST00000467746 N/A N/A 0.915±0.00 N/A N/A N/A N/A 0.291±0.00 N/A N/A N/A N/A N/A N/A
ENST00000470136 N/A N/A N/A 0.238±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000470808 N/A N/A N/A N/A N/A N/A N/A N/A 0.336±0.00 N/A N/A 0.514±0.00 N/A N/A
ENST00000484264 3.773±0.00 12.486±0.00 0.573±0.00 N/A 2.283±0.00 2.471±0.00 1.481±0.00 2.015±0.00 0.247±0.00 3.134±0.00 0.392±0.00 N/A N/A N/A
ENST00000484651 N/A N/A N/A N/A N/A N/A 0.249±0.00 0.187±0.00 N/A N/A N/A 0.248±0.00 N/A N/A
ENST00000485989 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.190±0.00 N/A N/A N/A
ENST00000493975 N/A N/A N/A N/A N/A 1.498±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000617535 N/A N/A N/A 0.125±0.00 N/A N/A N/A N/A N/A N/A 0.059±0.00 2.245±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007TX CIL_0007TX_0001 VISTA 4:1311752-1912379
CIL_0003K0 CIL_0003K0_0001 CGP 4:1715952-1745176
CIL_0006V2 CIL_0006V2_0001 CGP 4:1721490-1808872

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000226 IEA microtubule cytoskeleton organization
GO:0001666 IEA response to hypoxia
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0005813 IDA centrosome
GO:0008283 IEA cell proliferation
GO:0019904 IEA protein domain specific binding
GO:0021987 IEA cerebral cortex development
GO:0022008 IEA neurogenesis
GO:0022027 IEA interkinetic nuclear migration
GO:0030097 IEA hemopoiesis
GO:0030953 IEA astral microtubule organization
GO:0032886 IEA regulation of microtubule-based process
GO:0042994 IEA cytoplasmic sequestering of transcription factor
GO:0051726 IEA regulation of cell cycle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000005454 tacc3 transforming, acidic coiled-coil containing protein 3 protein_coding Danio_rerio
ENSMUSG00000037313 Tacc3 transforming, acidic coiled-coil containing protein 3 protein_coding Mus_musculus

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