C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: G protein-coupled receptor 124
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000020181 GPR124 9606 + 8:37784191-37844896 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000315215 GPR124-002 37796906-37844896 protein_coding
  ENST00000412232 GPR124-001 37797256-37843976 protein_coding
  ENST00000428068 GPR124-004 37784191-37829993 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000412232
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000412232 18.974±0.00 18.872±0.00 0.146±0.00 1.835±1.25 11.326±9.43 5.862±4.85 2.560±1.67 2.760±2.01 3.508±2.33 4.378±3.59 1.707±0.00 21.618±23.51 21.872±0.00 7.969±6.42

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000802 CIL_000802_0001 VISTA 8:37337791-37938686
CIL_0009C5 CIL_0009C5_0001 VISTA 8:37525567-38127835
CIL_0007QT CIL_0007QT_0001 VISTA 8:37525572-38127829
CIL_0002IW CIL_0002IW_0001 CGP 8:37762593-37844896
CIL_0002IX CIL_0002IX_0001 CGP 8:37784191-37849904

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0002040 ISS sprouting angiogenesis
GO:0004888 IEA transmembrane signaling receptor activity
GO:0004930 IEA G-protein coupled receptor activity
GO:0005515 IEA protein binding
GO:0005886 IEA plasma membrane
GO:0007166 IEA cell surface receptor signaling pathway
GO:0007186 TAS:IEA G-protein coupled receptor signaling pathway
GO:0007218 IEA neuropeptide signaling pathway
GO:0007417 ISS central nervous system development
GO:0009986 IEA cell surface
GO:0010595 IEA positive regulation of endothelial cell migration
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0043542 ISS endothelial cell migration
GO:0045765 ISS regulation of angiogenesis
GO:0050920 ISS regulation of chemotaxis
GO:0090210 IEA regulation of establishment of blood-brain barrier
GO:1900747 IEA negative regulation of vascular endothelial growth factor signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076994 gpr124 G protein-coupled receptor 124 protein_coding Danio_rerio
ENSMUSG00000031486 Gpr124 G protein-coupled receptor 124 protein_coding Mus_musculus

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