C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: G protein-coupled receptor 124
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000031486 Gpr124 10090 + 8:27085583-27123436 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000033876 Gpr124-001 27085598-27123436 protein_coding
  ENSMUST00000178514 Gpr124-002 27085583-27123435 protein_coding
  ENSMUST00000179207 Gpr124-003 27114133-27118834 nonsense_mediated_decay
  ENSMUST00000179351 Gpr124-005 27117369-27121623 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000033876ENSMUST00000178514ENSMUST00000179207ENSMUST00000179351
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000033876 19.150±13.78 4.852±1.75 16.743±3.68 3.675±1.32 5.018±2.00 6.497±2.20 2.632±0.53 6.693±0.97 1.303±0.57 8.675±3.64 0.466±0.09 12.164±6.90 5.965±3.30 0.353±0.03
ENSMUST00000178514 N/A 4.106±2.52 2.264±0.00 0.800±0.07 3.613±1.46 4.806±2.10 0.627±0.01 2.234±0.38 0.313±0.04 5.953±3.16 0.283±0.00 12.366±7.71 3.010±0.00 0.118±0.11
ENSMUST00000179207 N/A N/A N/A 3.049±0.00 N/A N/A N/A N/A N/A N/A N/A 6.155±0.00 3.529±1.81 N/A
ENSMUST00000179351 N/A 6.479±0.55 N/A N/A 9.304±2.79 7.657±0.99 N/A N/A N/A 12.534±1.20 N/A 21.816±2.49 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000802 CIL_000802_0002 VISTA 8:26613996-27214881
CIL_0009C5 CIL_0009C5_0002 VISTA 8:26806327-27408431
CIL_0007QT CIL_0007QT_0002 VISTA 8:26806345-27408424
CIL_0002IW CIL_0002IW_0002 CGP 8:27042555-27123436
CIL_0002IX CIL_0002IX_0002 CGP 8:27085583-27128632

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IMP angiogenesis
GO:0002040 IMP sprouting angiogenesis
GO:0004930 IEA G-protein coupled receptor activity
GO:0005886 ISO plasma membrane
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007218 IEA neuropeptide signaling pathway
GO:0007417 IMP central nervous system development
GO:0009986 IDA cell surface
GO:0010595 IDA positive regulation of endothelial cell migration
GO:0016021 IEA integral component of membrane
GO:0043542 IMP endothelial cell migration
GO:0045765 IMP regulation of angiogenesis
GO:0050920 IMP regulation of chemotaxis
GO:0090210 IMP regulation of establishment of blood-brain barrier
GO:1900747 IMP negative regulation of vascular endothelial growth factor signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076994 gpr124 G protein-coupled receptor 124 protein_coding Danio_rerio
ENSG00000020181 GPR124 G protein-coupled receptor 124 protein_coding Homo_sapiens

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