C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: G protein-coupled receptor 124
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000412232 GPR124-001 ENSG00000020181 9606 + 8:37797256-37843976 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000412232
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000412232 18.974±0.00 18.872±0.00 0.146±0.00 1.835±1.25 11.326±9.43 5.862±4.85 2.560±1.67 2.760±2.01 3.508±2.33 4.378±3.59 1.707±0.00 21.618±23.51 21.872±0.00 7.969±6.42

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000802 CIL_000802_0001 VISTA 8:37337791-37938686
CIL_0009C5 CIL_0009C5_0001 VISTA 8:37525567-38127835
CIL_0007QT CIL_0007QT_0001 VISTA 8:37525572-38127829
CIL_0002IW CIL_0002IW_0001 CGP 8:37762593-37844896
CIL_0002IX CIL_0002IX_0001 CGP 8:37784191-37849904

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0002040 ISS sprouting angiogenesis
GO:0004888 IEA transmembrane signaling receptor activity
GO:0004930 IEA G-protein coupled receptor activity
GO:0005515 IEA protein binding
GO:0005886 IEA plasma membrane
GO:0007166 IEA cell surface receptor signaling pathway
GO:0007186 TAS:IEA G-protein coupled receptor signaling pathway
GO:0007218 IEA neuropeptide signaling pathway
GO:0007417 ISS central nervous system development
GO:0009986 IEA cell surface
GO:0010595 IEA positive regulation of endothelial cell migration
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0043542 ISS endothelial cell migration
GO:0045765 ISS regulation of angiogenesis
GO:0050920 ISS regulation of chemotaxis
GO:0090210 IEA regulation of establishment of blood-brain barrier
GO:1900747 IEA negative regulation of vascular endothelial growth factor signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000033876 Gpr124-001 protein_coding Mus_musculus 0 3906
ENSMUST00000178514 Gpr124-002 protein_coding Mus_musculus 0 1825
ENSMUST00000179207 Gpr124-003 nonsense_mediated_decay Mus_musculus 0 532
ENSMUST00000179351 Gpr124-005 protein_coding Mus_musculus 0 252
ENSDART00000123547 GPR123 (3 of 3)-201 protein_coding Danio_rerio 4e-34 152

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